Pancreatitis is a disease caused by inflammation of the pancreas. The pancreas is a small fleshy organ between the stomach and the small intestine. The pancreas has many functions related to digestion and the regulation of blood sugar levels.
Dogs with severe, sudden-onset pancreatitis are often very ill and show signs of vomiting, lethargy, loss of appetite, abdominal pain, and fever. Dogs with less severe forms of pancreatitis may show only mild signs of illness, and some dogs may have low-grade ongoing problems with recurring episodes of illness.
Is your furry friend acting strange lately? Loss of appetite, vomiting, or just looking miserable? These could be signs of pancreatitis – a serious condition that needs quick attention. As a pet parent who’s been through this scary experience, I want to share everything you need to know about how vets test for pancreatitis in dogs.
What Even Is Pancreatitis Anyway?
Before diving into testing, let’s understand what we’re dealing with. The pancreas is this small but mighty organ tucked near your dog’s stomach and intestines. It has two super important jobs:
- Endocrine function: Produces insulin and glucagon to control blood sugar
- Exocrine function: Makes digestive enzymes (like amylase and lipase) that help break down food
When your dog has pancreatitis, their pancreas becomes inflamed and those digestive enzymes activate too early – inside the pancreas rather than in the intestines where they belong. This causes the enzymes to start digesting the pancreas itself and surrounding tissues. Ouch!
Pancreatitis comes in two flavors
- Acute pancreatitis: Comes on suddenly, often after eating something fatty
- Chronic pancreatitis: Develops slowly over time, sometimes from repeated acute attacks
Warning Signs Your Dog Might Have Pancreatitis
Before we rush to testing, let’s talk about what might send you to the vet in the first place. These symptoms could indicate your pup has pancreatitis:
- Repeated vomiting (this is super common)
- Loss of appetite or flat-out refusing to eat
- Weakness or acting listless
- Abdominal pain (they might stand with a hunched back)
- Diarrhea
- Dehydration (sunken eyes, dry nose, thick saliva)
- Fever
If your dog is showing these signs, especially after gobbling up some fatty table scraps or getting into the trash, don’t wait – call your vet ASAP!
How Vets Diagnose Pancreatitis in Dogs
When you bring your fur baby to the vet with suspected pancreatitis, they’ll typically perform several tests to confirm the diagnosis and rule out other conditions Here’s what the testing process usually looks like
1. Physical Examination
First things first – your vet will do a thorough physical exam. They’ll:
- Check your dog’s temperature
- Feel their abdomen (which might be painful)
- Look at their gums for signs of dehydration
- Listen to their heart
- Ask about recent diet and behavior changes
2. Blood Tests
Blood tests are SUPER important for diagnosing pancreatitis. The most common ones include:
a) Pancreatic Lipase Immunoreactivity (PLI)
This is the gold standard test for pancreatitis in dogs! It measures a specific enzyme that leaks from the inflamed pancreas.
There are two versions:
- cPLI (canine pancreatic lipase immunoreactivity) for dogs
- fPLI (feline pancreatic lipase immunoreactivity) for cats
Your vet might use a quick in-clinic version called SNAP cPL, which gives a simple “normal” or “abnormal” result. For more precise measurements, they’ll send blood to a reference laboratory.
b) Complete Blood Count (CBC)
This test checks for:
- Increased white blood cells (sign of inflammation)
- Changes in red blood cell counts (possible dehydration)
c) Serum Biochemistry Profile
This comprehensive panel can show:
- Elevated amylase and lipase (traditional pancreatic enzymes)
- Liver and kidney values (to check if other organs are affected)
- Blood sugar levels (important since the pancreas regulates this)
d) Vitamin B12 and Folate
These vitamin levels can provide supporting evidence of exocrine pancreatic insufficiency, which can develop after pancreatitis damages the pancreas.
3. Imaging Tests
While blood tests are important, imaging helps your vet actually see what’s happening inside.
a) X-rays
X-rays don’t show the pancreas directly but can help rule out other causes of similar symptoms (like intestinal blockages). They might show changes in the area where the pancreas is located.
b) Ultrasound
This is way more helpful than X-rays for pancreatitis! An ultrasound can:
- Show inflammation of the pancreas
- Detect masses or cysts
- Rule out other conditions
- Help guide a needle if a sample needs to be taken
4. Fine Needle Aspirate
In some cases, your vet might use a small needle to collect a sample of cells from the pancreas to examine for inflammation or infection. This is less common but useful in complex cases.
5. Surgical or Laparoscopic Biopsy
This is typically the last resort if other tests are inconclusive or if there’s a suspected mass on the pancreas. It’s more invasive but provides definitive answers.
Why Proper Testing Matters So Much
I can’t stress enough how important accurate diagnosis is! Pancreatitis can be mistaken for other conditions that cause vomiting and abdominal pain. Without proper testing, your pup might not get the right treatment.
Also, pancreatitis can damage other organs if left untreated. The enzymes that leak from the pancreas can cause multi-organ failure in severe cases. That’s why quick and accurate testing is crucial.
Treatment After Diagnosis
Once your vet confirms pancreatitis through testing, treatment typically involves:
- IV fluids for dehydration (if severe)
- Pain medications
- Anti-nausea meds
- Withholding food initially (if they can’t keep anything down)
- Gradual introduction of a low-fat diet
- In severe cases, hospitalization for a few days
There’s even a special medication called Fuzapladib sodium (Panoquell-CA1) specifically for dogs with rapid-onset pancreatitis that helps prevent ongoing inflammation.
Preventing Future Episodes
After your dog recovers, your vet will likely recommend:
- A permanent low-fat diet (possibly prescription food)
- Small, frequent meals instead of large ones
- Strict avoidance of table scraps and fatty treats
- Regular check-ups to monitor pancreatic enzyme levels
Some supplements that might help prevent recurrence include:
- Digestive enzyme supplements
- Fish oil (though talk to your vet first since these are high in fat)
Our Experience With Pancreatitis Testing
We went through this with our schnauzer, Baxter, last year after Thanksgiving (one of the busiest times for pancreatitis in dogs!). Someone at our family gathering slipped him some turkey skin, and two days later, he was vomiting and refusing to eat.
The vet suspected pancreatitis immediately because of his breed (schnauzers are prone to it) and the timing after a holiday meal. They did blood tests including the cPLI test, which came back elevated. An ultrasound confirmed inflammation in his pancreas.
After three days in the animal hospital on IV fluids, Baxter came home and has been on a low-fat prescription diet ever since. We’ve had no more episodes, thank goodness!
Which Dogs Are Most At Risk?
Some dogs are more likely to develop pancreatitis than others:
- Breeds: Miniature Schnauzers, Yorkshire Terriers, Cocker Spaniels, Dachshunds, Poodles, and some sled dog breeds
- Overweight dogs
- Dogs with other conditions like diabetes, hypothyroidism, or Cushing’s syndrome
- Dogs who’ve had pancreatitis before
- Garbage-raiders and table-scrap beggars
Final Thoughts
If your dog is showing signs of pancreatitis, don’t wait to get them tested! Early diagnosis through proper testing can make all the difference in their recovery.
Remember: the most reliable test is the pancreatic lipase immunoreactivity (PLI) test, but your vet will likely use a combination of blood tests and imaging to get the full picture.
Have you gone through pancreatitis testing with your dog? I’d love to hear your experiences in the comments below!
Disclaimer: While I’ve done my best to provide accurate information, I’m not a veterinarian. Always consult your vet for proper diagnosis and treatment of your pet’s health conditions.

What is pancreas-specific lipase? How is it different from serum lipase?
A pancreas-specific lipase is a form of lipase produced only in the pancreas. It is highly specific to the pancreas, and blood values increase only when pancreatic inflammation occurs. By comparison, serum lipase can come from tissues other than the pancreas, and high blood values can occur with conditions other than pancreatitis.
Does the sample have to be sent away to a diagnostic laboratory?
A version of the cPLI test can be used in-clinic (SNAP cPL© from IDEXX). This rapid “pet-side” test takes only a few minutes and can indicate whether pancreatitis could be the cause of a pet’s illness. Ideally, the sample should also be sent to the laboratory to get an actual value of cPLI. This will help confirm the diagnosis of pancreatitis and provide a starting point or baseline that can be used to monitor the pet’s progress after treatment has been started.
Pancreatitis in the dog. Dr. Dan explains.
FAQ
How is pancreatitis diagnosed in dogs?
Overall, blood testing and abdominal ultrasounds are better in helping to diagnose pancreatitis in dogs when it’s a acute and severe case. Treatment of pancreatitis in dogs is primarily supportive care regardless of whether the patient has acute or chronic pancreatitis. Treatment for pancreatitis may include the following:
Can a veterinarian test for pancreatitis?
Routine blood tests are often not helpful, but there are pancreatic-specific blood tests that can be performed when a veterinarian has a high suspicion of pancreatitis. A thorough physical exam is important to rule out other health conditions with similar symptoms.
Can a dog be tested for pancreatic insufficiency?
However, if a dog has concurrent pancreatitis or if a sample is taken shortly after a meal, the amount of trypsin-like immunoreactivity may be temporarily increased into the normal range. For this reason, the pet must be fasted prior to testing. Are there any other tests that may be used to diagnose exocrine pancreatic insufficiency?
What tests are used to diagnose pancreatitis?
Bloodwork:This measures blood cells, blood sugar, electrolytes, and organ function parameters. Blood tests:Blood tests for pancreatic enzymes can help diagnose pancreatitis, including a specific test called canine pancreatic lipase immunoreactivity (cPLI).
How can I tell if my cat has pancreatitis?
Cats with pancreatitis may become quiet rather than act painful. Ultrasound and X-rays are the most common imaging tests for diagnosing pancreatitis in a general practice. Looking for signs of an obstruction is often the reason we take X-rays in such cases.
What should I do if my dog has pancreatitis?
Follow your vet’s instructions. Even if your pup seems better, it’s important that you take them for all their recommended follow-up visits and tests. Pancreatitis can happen again, so it’s vital you follow your vet’s advice, especially about food. And make sure your buddy finishes the medicines their vet prescribed.
How do vets diagnose pancreatitis in dogs?
What is the red flag for pancreatitis?
Pancreatitis red flags include severe, steady pain in the upper/middle abdomen that may radiate to the back, nausea, vomiting, fever, and abdominal tenderness. Yellowing of the skin and eyes (jaundice) and a rapid heart rate also indicate potential complications. These symptoms can signal a serious condition requiring immediate medical attention and hospitalization.
How much does a dog pancreatitis test cost?
You can expect your vet to administer certain diagnostics when you bring your dog in for pancreatitis symptoms. This will result in the following costs: Canine pancreatic lipase immunoreactivity test (blood analysis): $40 to $80 per panel. Abdominal ultrasound: $300 to $350.
What can be mistaken for pancreatitis in dogs?