Human Pain Relievers for Dogs: What’s Safe and What’s Dangerous

September 17, 2025 |

However, as our four-legged companions start to live longer lives, they’re more at risk for disease and discomfort. Luckily, there’s several options available to help—including pain relief and pain management for dogs.

In this article, you’ll learn to recognize signs of pain in dogs and how to treat pain in dogs.

You’ll also understand which pain medications are safe for them and whether they need a prescription from their vet, or if you can get them over the counter.

Ever caught your furry friend limping or whining in pain and wondered if you could just give them one of your pain pills? I’ve been there too. It’s heartbreaking to see our four-legged family members suffer, and the temptation to reach for our medicine cabinet is real—especially when it’s late at night or the vet is closed.

But here’s the crucial truth you need to know: Dogs process medications completely differently than humans do. What helps us might seriously harm them.

In this comprehensive guide, I’ll walk you through everything you need to know about pain relief options for your canine companion, including which medications are safe (spoiler: very few human meds are), proper dosages, and what to do in emergency situations.

The Golden Rule: Never Give Human Pain Pills to Dogs Without Vet Approval

Before diving into specifics, let me be crystal clear: never give your dog any human pain medication without veterinary guidance. Dogs’ bodies process drugs differently than ours, and what’s harmless to us can be deadly to them.

Most human pain relievers can cause serious health problems or even death in dogs because they contain ingredients that are toxic to their systems. For example certain chemicals found in human medicine like acetaminophen, cannot be broken down by a dog’s body and can slowly destroy their liver.

What About Those Emergency Situations?

If your dog is showing signs of severe pain like:

  • Inability to stand
  • Extreme weakness
  • Persistent crying or whining
  • Visible distress

Don’t wait and don’t experiment with medications. Seek emergency veterinary care immediately. Many emergency vet clinics operate 24/7 and can provide appropriate safe pain relief for your pet.

FDA-Approved Pain Medications for Dogs

The safest approach is always to use medications specifically designed for canines and approved by the Food and Drug Administration (FDA) These drugs have been tested on dogs and proven both safe and effective when used correctly,

Here are the only NSAIDs (non-steroidal anti-inflammatory drugs) approved by the FDA for dogs:

Generic Name Brand Names
Carprofen Novox, Rimadyl, Carpox, Norocarp
Deracoxib Deramaxx, Ostimax, Doxidyl
Firocoxib Previcox, Firox
Grapiprant Galliprant
Meloxicam Metacam, Loxicom, OroCAM
Robenacoxib Onsior (for no more than 3 days)

These medications require a veterinary prescription and shouldn’t be given without proper veterinary guidance.

Human Medications Sometimes Used for Dogs (Veterinary Supervision Required)

There are a few human medications that veterinarians might occasionally prescribe for dogs, but only under their close supervision and specific dosing instructions. These should never be given without consulting your vet first:

Buffered Aspirin

Sometimes vets recommend buffered aspirin for dogs with arthritis pain. However, it’s not generally the first choice, and many other dog-specific NSAIDs are available that work better with fewer side effects.

Benadryl (Diphenhydramine)

Benadryl is sometimes used in veterinary practice to treat allergies, motion sickness, and travel anxiety. However, there have been cases of diphenhydramine poisoning in dogs, so proper dosing is critical.

Pepto-Bismol

This falls into a similar category as other over-the-counter meds—it can be safe for certain breeds with specific conditions, but only under veterinary supervision. If your dog has diarrhea or an upset stomach, it’s best to use dog-specific medications or treatments.

Tagamet (Cimetidine)

Cimetidine is sometimes prescribed as an extra-label drug in veterinary medicine to treat gastritis, reflux, and esophagitis. It can also be used for treating mast cell tumors in dogs.

Human Pain Medications That Are Dangerous for Dogs

Now let’s talk about the human pain relievers that should NEVER be given to dogs:

Ibuprofen (Advil, Motrin)

Ibuprofen is extremely toxic to dogs and can cause:

  • Seizures
  • Heart problems
  • Stomach ulcers
  • Kidney failure
  • Impaired balance
  • Low blood pressure

Even small doses can be dangerous, and larger doses can be fatal.

Naproxen (Aleve)

Naproxen is even more toxic than ibuprofen for dogs. It can cause:

  • Vomiting
  • Ulcers
  • Anemia
  • Black, bloody stools
  • Kidney failure

Acetaminophen (Tylenol)

Acetaminophen can cause liver damage, vomiting, and heart problems in dogs. It’s particularly dangerous because it can cause symptoms that aren’t immediately obvious until serious damage has occurred.

Other Options for Pain Relief in Dogs

If your dog is experiencing pain, there are several vet-approved options beyond standard pain medications:

Prescription Medications for Nerve Pain

For certain types of pain, especially chronic or nerve-related pain, your vet might prescribe:

  • Gabapentin
  • Amantadine
  • Pregabalin

Natural Supplements (Vet-Approved)

Some natural supplements may help with pain management, particularly for arthritis and joint pain:

  • Glucosamine and chondroitin: May reduce inflammation and help cartilage repair itself
  • Fish oil supplements: Contain omega-3 fatty acids that can help slow down joint degeneration
  • Green-lipped mussels: Can boost cartilage and reduce inflammation
  • Turmeric/Curcumin: May have anti-inflammatory effects at appropriate doses

Always discuss these supplements with your vet before starting them, as they can interact with other medications or might not be appropriate for your dog’s specific condition.

Alternative Therapies

Several non-medication approaches might help manage your dog’s pain:

  • Acupuncture: Particularly successful for myofascial pain and arthritis
  • Medical massage: Can help relax muscles and joints
  • Cold or heat therapy: Applying cold packs for swelling or heat for chronic pain
  • Shock wave therapy: Uses sound waves to promote healing
  • Platelet-rich plasma therapy: May help with severely affected joints

Signs Your Dog Is in Pain

Dogs can’t tell us when they’re hurting, so it’s important to recognize the signs:

  • Limping or difficulty moving
  • Reluctance to jump, climb stairs, or play
  • Excessive licking of a particular area
  • Changes in appetite
  • Unusual aggression or withdrawal
  • Panting or restlessness
  • Whimpering or crying

What To Do If You Suspect Your Dog Is in Pain

  1. Call your veterinarian immediately. Describe the symptoms and follow their advice.
  2. Don’t give any medication without veterinary guidance.
  3. Keep your dog comfortable until you can get professional help. This might mean restricting movement or providing a quiet, comfortable place to rest.
  4. Monitor vital signs if possible, including breathing rate and gum color.
  5. Transport carefully to the vet if needed, minimizing movement that could cause additional pain.

My Personal Experience

Last year, my Golden Retriever Max was limping after a particularly enthusiastic game of fetch. It was Sunday evening, and my first instinct was to give him a baby aspirin—something I’d heard was “safe” for dogs. But instead, I called our emergency vet line, and I’m so glad I did.

The vet explained that even “safe” human medications can be dangerous without proper dosing, and Max might have had underlying issues that would make certain meds risky. We ended up getting a proper examination the next morning, and Max was prescribed an appropriate canine pain reliever that worked wonders without any side effects.

Preventative Care

The best way to handle pain in dogs is to prevent it when possible:

  • Regular vet check-ups to catch issues early
  • Maintaining a healthy weight to reduce strain on joints
  • Appropriate exercise for your dog’s age and breed
  • Proper nutrition including joint supplements if recommended by your vet
  • Safe environments that minimize the risk of injury

Final Thoughts

While we hate to see our dogs in pain, giving them human medications without veterinary guidance puts them at serious risk. The safest approach is always to consult with a vet who can prescribe appropriate medications specifically designed for dogs.

Remember: our furry friends depend on us to make the right decisions for their health. When in doubt, always call your vet rather than experimenting with medications that could do more harm than good.

Have you ever been tempted to give your dog human pain relievers? What did you do instead? I’d love to hear your experiences in the comments!

Disclaimer: This article is for informational purposes only and is not intended to replace professional veterinary advice. Always consult with your veterinarian before giving your dog any medication.

what human pain relievers are safe for dogs

Are Human Pain Meds Safe for Dogs?

There are a few medications that humans and dogs can both take, such as certain heart medications, thyroid medications, and antibiotics.

However, even if a medication is safe for dogs, the dosing is usually different from a human’s. Additionally, the form in which the medication is carried—such as the capsule or the additive to make a tablet—might be toxic or harmful to your pet.

A human’s metabolism is also much different than a dog’s. Because of this, some medications that are safe for people can be toxic to dogs, or even fatal.

Never give your dog these common over-the-counter human pain relievers:

  • Acetaminophen (Tylenol™)
  • Ibuprofen (Advil™ or Motrin™)
  • Naproxen (Aleve®)

Always ask your vet before giving your dog any human medication.

Other Pain Meds for Dogs

Other pain meds your vet may prescribe for your pup are:

  • Tramadol
  • Amantadine
  • Librela™

Are Human Pain Medications Safe For Dogs? Advil, Aspirin, etc.

FAQ

Are NSAIDs safe for dogs?

While technically, it can be one of the safe human meds for dogs, many other (and better) dog-specific NSAIDs are available for pain. There are even less potent pain relievers that are safer for dogs to take than you can procure from your vet.

Are human pain medications safe for dogs?

However, there are some human pain medications that are generally considered safe for dogs when used under the guidance of a veterinarian. One of the most commonly used human pain medications for dogs is nonsteroidal anti-inflammatory drugs (NSAIDs).

What can I give my Dog for pain?

With your vet’s guidance, you may need to try different things to find out what brings the most relief. Dogs can benefit from taking pain medicines such as NSAIDs, narcotics, steroids, nerve pain medicines, and natural supplements. Sometimes, vets prescribe human medications, such as opioids, to dogs.

Can you give a dog Painkiller?

However, you can’t give these drugs to your dog or puppy: No human painkillers are safe for dogs. You can only give your dog pain medications specifically designed for canines and approved by the Food and Drug Administration (FDA). These drugs also have to be prescribed by a vet, since there are no FDA-approved OTC painkillers for dogs.

Is medication safe for dogs?

However, even if a medication is safe for dogs, the dosing is usually different from a human’s. Additionally, the form in which the medication is carried—such as the capsule or the additive to make a tablet—might be toxic or harmful to your pet. A human’s metabolism is also much different than a dog’s.

Are there natural alternatives to human pain medications for dogs?

Yes, there are several natural alternatives to human pain medications for dogs, including acupuncture, massage therapy, herbal supplements, and CBD oil. These options can be effective in managing pain and inflammation in dogs, but it’s important to consult with your veterinarian before trying any new treatments. 4.

What human pain reliever is ok for dogs?

Unless under the explicit direction of a trusted veterinarian, dogs should not be given human medications like ibuprofen (Advil), acetaminophen (Tylenol), or aspirin. Ibuprofen has a narrow margin of safety in dogs. One recommended dosage is 5 mg/kg/day, divided.

What can I give my dog for immediate pain relief?

Nonsteroidal anti-inflammatory drugs, or NSAIDs, help reduce swelling, stiffness, and joint pain in humans, and they can do the same for your dog. There are some of the available NSAIDs just for dogs: carprofen (Novox or Rimadyl) deracoxib (Deramaxx) firocoxib (Previcox) meloxicam (Metacam )

Can I give my dog any painkillers without a vet?

You give whatever the vet prescribed for him. Human over the counter painkillers are neither safe nor effective when used in dogs for pain. Human medications should be taken by humans only.

Can you give anything to a dog in pain?

Dogs need veterinary-prescribed pain medications only; human pain pills can cause serious harm or death.Jun 17, 2025