Do Dogs Lose Their Hair During Chemo? The Complete Guide for Pet Parents

October 1, 2025 |

When your furry friend gets diagnosed with cancer, it’s natural to have a million questions racing through your mind. One of the most common concerns I hear from pet parents is: “Will my dog lose all their hair during chemotherapy?” This worry stems from what we know about human cancer treatment, where hair loss is practically expected.

But here’s the good news – dogs experience chemotherapy very differently than humans do! As someone who’s helped many pet owners through this journey, I want to share what you really need to know about canine hair loss during cancer treatment.

The Truth About Dogs and Chemo Hair Loss

Myth vs. Reality

Let’s start by busting the biggest myth:

MYTH: All dogs lose their fur during chemotherapy, just like humans lose their hair.
REALITY: Most dogs actually keep their fur during chemotherapy! Hair loss in dogs receiving cancer treatment is relatively uncommon.

I remember when my neighbor’s golden retriever went through lymphoma treatment She was so worried about her dog becoming completely bald, but was pleasantly surprised when he maintained his beautiful coat throughout the entire treatment process

Which Dogs Are More Likely to Lose Hair?

While most dogs keep their fur certain breeds are more susceptible to hair loss during chemo

  • Dogs with continuously growing hair (poodles, bichons, etc.)
  • Dogs with wiry coats (many terrier breeds)
  • Dogs with curly hair (poodles, old English sheepdogs)

According to research from Tufts University, approximately 1 in 5 dogs experienced some hair loss during treatment with the chemotherapy drug doxorubicin. The study found that dogs with curly or wiry hair were significantly more likely to lose their hair compared to dogs with straight coats.

Why does this happen? It’s all about the hair follicles!

The Science Behind Chemo and Fur Loss

It’s All About the Hair Follicles

The reason for the difference comes down to how hair grows. Chemotherapy targets rapidly dividing cells (which is why it works against cancer). Hair follicles that are actively growing are some of the fastest dividing cells in the body.

Dogs with continuously growing coats have a higher percentage of hair follicles in the active growth phase at any given time, making them more vulnerable to chemo’s effects. Their hair follicles more closely resemble human hair follicles.

Meanwhile, dogs with straight coats (like Labradors, Rottweilers, and German shepherds) have most of their hair follicles in a resting phase, which is why they typically keep their fur during treatment.

What Hair Loss Might Look Like

If your dog does experience hair loss during chemo, you might notice:

  • Loss of whiskers and eyebrows (most common)
  • Thinning of the coat
  • Patches of hair loss
  • Slow regrowth where fur was shaved for IV catheter placement
  • Complete hair loss (rare, mainly in non-shedding breeds)

Other Coat Changes During Chemo

Hair loss isn’t the only change you might notice in your dog’s coat during treatment. Some other possible changes include:

  • Color changes: Some dogs’ fur may lighten or darken
  • Texture changes: The fur might feel different to the touch
  • Slow regrowth: Areas shaved for treatment might take longer to grow back
  • Loss of guard hairs: The coarser outer hairs might fall out

Side Effects of Canine Chemotherapy

While we’re focused on hair loss, it’s worth understanding the overall side effect profile of chemotherapy in dogs.

Good News: Dogs Experience Fewer Side Effects Than Humans

Veterinary chemotherapy is given at significantly lower doses than human chemotherapy. The goal for pets is different – we aim for quality of life rather than cure at all costs.

The stats are reassuring:

  • Approximately 80% of dogs have NO side effects from chemotherapy
  • Only 15-20% experience mild to moderate side effects lasting a few days
  • Less than 5% have serious complications like severe vomiting or diarrhea

These facts often surprise pet parents who fear their dog will suffer terribly during treatment.

Special Care for Dogs During Chemo

Grooming Tips for Dogs Undergoing Chemotherapy

If your dog is undergoing chemotherapy, here are some grooming tips to keep them comfortable:

  • Choose gentle shampoos: Avoid products with artificial colors, fragrances, or metals (zinc, silver)
  • Skip formaldehyde preservatives: Look out for “slow-releasing compounds” on labels
  • Avoid coconut byproducts: Some coconut derivatives (Mea/Cocomide Dea) may be problematic
  • More frequent, gentle cleaning: Sponge baths might be better than full baths
  • Clean any discharge promptly: If your dog has any reaction to medication

Special Considerations for Cutaneous Lymphoma

If your dog has cutaneous lymphoma (skin lymphoma), you’ll need to be extra careful with grooming because the cancer directly affects the skin. This type can cause:

  • Lesions that may ooze fluid
  • Itchiness and irritation
  • Thickening of the skin
  • Hair loss directly related to the cancer itself

Your vet will provide specific instructions for cleaning and caring for affected areas.

What About Radiation Therapy?

If your dog is receiving radiation therapy rather than (or in addition to) chemotherapy, be aware that:

  • Radiation passes through the skin to reach tumors
  • Products on your dog’s skin can potentially interfere with treatment
  • Metal-containing shampoos should be avoided before radiation treatments
  • Always follow your veterinary oncologist’s specific instructions

What to Expect After Chemotherapy Ends

The good news is that any hair loss from chemotherapy is temporary! Once treatment ends, your dog’s coat should grow back normally, though it might take some time.

Some pet parents even report that their dog’s new coat comes in slightly different – sometimes softer, curlier, or even a different shade than before. My client’s schnauzer grew back a slightly lighter coat after her lymphoma treatment, which was unexpected but kinda cute!

Personalized Cancer Treatment for Your Dog

Every dog responds differently to cancer and its treatments. That’s why personalized approaches are becoming more common in veterinary oncology.

Advanced testing can now predict which drugs will be most effective against your dog’s specific cancer cells. This means your vet can choose the most effective treatment right from the start, potentially reducing unnecessary side effects (including hair loss) from ineffective drugs.

Tips for Supporting Your Dog Through Cancer Treatment

  1. Keep routines normal: Dogs thrive on routine, so maintain walks and playtime as much as possible
  2. Watch for side effects: Know what’s normal and what needs immediate attention
  3. Focus on nutrition: Some dogs may need diet adjustments during treatment
  4. Reduce stress: Create a calm environment at home
  5. Celebrate small victories: Every good day is worth celebrating!

When to Call Your Vet

While most side effects are mild, you should contact your vet immediately if your dog experiences:

  • Severe vomiting (more than 3 times in 24 hours)
  • Diarrhea that lasts more than 24 hours
  • Refusal to eat for more than 24 hours
  • Lethargy or extreme weakness
  • Fever
  • Unusual bleeding

FAQ About Dogs and Hair Loss During Chemo

Does chemotherapy dose affect hair loss?

Yes! Research has found that dogs receiving higher cumulative doses of chemotherapy drugs (particularly doxorubicin) are more likely to experience hair loss.

Will my dog be uncomfortable if they lose their hair?

Most dogs don’t seem bothered by hair loss itself. However, they may need protection from sun or cold if they lose significant amounts of fur.

Can I prevent my dog’s hair loss during chemotherapy?

Currently, there aren’t proven methods to prevent chemotherapy-induced hair loss in dogs. Research in this area continues, and what we learn might even help human cancer patients one day!

Should I stop my dog’s treatment if they lose hair?

Hair loss alone is not a reason to stop treatment. Always discuss concerns with your veterinary oncologist before making treatment decisions.

Final Thoughts

Remember that most dogs keep their beautiful coats throughout treatment, and even those who do experience hair loss will grow it back. The most important thing is focusing on your pup’s quality of life during this challenging time.

Have you had experience with a dog going through chemotherapy? I’d love to hear your story in the comments below!

do dogs lose their hair during chemo

Why dogs and cats don’t lose their fur during chemotherapy #podcastclips