How Do Dogs Know You Have Low Blood Sugar? Incredible Canine Detection Abilities Explained

September 27, 2025 |

Have you ever wondered how your furry friend seems to know when something’s wrong with you before you do? It’s not just your imagination – dogs really can detect when humans have low blood sugar, and it’s pretty amazing how they do it!

As someone who’s been researching canine medical detection abilities for years, I’ve been fascinated by this incredible skill. Today, I’m gonna share everything I know about how dogs detect hypoglycemia and why they might just be the best early warning system for people with diabetes.

The Remarkable Sense of Smell: Dogs’ Superpower

Dogs have always been known for their incredible sense of smell. But just how powerful is it? Well, while humans have about 6 million olfactory receptors in our noses, dogs have a whopping 300 million! Plus, the part of their brain dedicated to analyzing smells is proportionally 40 times larger than ours.

This super-smell ability is what allows them to

  • Detect drugs at airports
  • Find missing persons
  • Hunt prey
  • And yes, detect changes in your body chemistry

How Dogs Detect Low Blood Sugar: The Science Behind It

For years, scientists knew dogs could alert their owners to hypoglycemic events, but they weren’t exactly sure what the dogs were smelling Recent research has shed light on this mystery

The Isoprene Connection

According to research published in Pharmacy Times, dogs are likely detecting a chemical compound called isoprene in human breath. When blood sugar drops to dangerous levels, isoprene levels rise significantly – sometimes almost doubling.

In one study researchers gradually lowered blood sugar levels in women with type 1 diabetes under controlled conditions. Using mass spectrometry, they detected that isoprene levels rose dramatically at the onset of hypoglycemia.

While scientists believe elevated isoprene is a byproduct of cholesterol production, they’re still investigating exactly why levels of this chemical rise during hypoglycemic events. What’s clear is that dogs are highly sensitive to this change.

Other Possible Detection Methods

Dogs may also be picking up on:

  1. Behavioral changes – Subtle changes in your movement, attention, or energy level
  2. Sweat composition – Changes in your sweat chemistry during hypoglycemia
  3. Visual cues – Dogs are extremely attentive to human body language

Signs Your Dog May Be Alerting You to Low Blood Sugar

If you have diabetes, your dog might already be trying to alert you to blood sugar changes without formal training. Here are some common alert behaviors:

  • Pawing or nudging you persistently
  • Licking your face or hands
  • Whining or barking
  • Following you more closely than usual
  • Acting agitated or restless
  • Staring at you intently
  • Fetching diabetes supplies

My neighbor’s Jack Russell Terrier started waking her up in the middle of the night whenever her blood sugar was dropping dangerously low – all without any formal training! Dogs are just that intuitive.

Can Any Dog Be Trained to Detect Low Blood Sugar?

While many dogs have the natural ability to detect these changes, some breeds tend to excel at this task:

Breed Characteristics Helpful for Detection
Labrador Retrievers Excellent nose, trainable, calm temperament
Golden Retrievers Highly sensitive, eager to please, focused
German Shepherds Intelligent, trainable, attentive to owners
Poodles Smart, hypoallergenic, highly trainable
Border Collies Extremely intelligent, observant, high energy

That said, mixed breeds can be equally effective! The most important factors are:

  • A good nose (most dogs have this!)
  • Trainability and focus
  • Bond with their handler
  • Motivation to alert

Formal Medical Alert Dog Training

If you’re interested in a trained diabetes alert dog, be aware that proper training takes time and expertise. These dogs typically:

  1. Are exposed to samples of sweat, breath, or saliva collected during hypoglycemic events
  2. Learn to associate these scents with rewards
  3. Are taught specific alert behaviors like pawing, fetching a meter, or pressing an alert button
  4. Practice alerting in various environments with increasing distractions
  5. Train extensively with their future owner

This specialized training can take 6-12 months and costs between $8,000-$25,000, depending on the organization. Some nonprofits provide these dogs at reduced costs to those who qualify.

What Should You Do When Your Dog Alerts?

If your dog is alerting you to possible low blood sugar:

  1. Check your blood glucose levels immediately
  2. If levels are indeed low, take glucose tablets or consume fast-acting carbohydrates
  3. Reward your dog for the alert (even if your blood sugar wasn’t actually low)
  4. Wait 15 minutes and recheck your levels
  5. If still low, repeat treatment

What To Give a Dog With Low Blood Sugar

Interestingly, dogs themselves can experience hypoglycemia too! If your dog is showing signs of low blood sugar (weakness, lethargy, trembling, seizures), here’s what you can give them:

  • Honey or maple syrup: Can be quickly absorbed and raise blood sugar levels
  • Glucose gel: Specifically designed for quick blood sugar elevation
  • Sugar water: A small amount of sugar dissolved in water
  • High-carb dog food: Helps stabilize blood sugar
  • Corn syrup: Another quick option in emergency situations
  • Peanut butter: Provides quick energy

However, always consult your vet if your dog experiences frequent hypoglycemic episodes, as this could indicate an underlying health condition.

Beyond Diabetes: Other Conditions Dogs Can Detect

The amazing scent capabilities of dogs extend beyond just detecting low blood sugar. These remarkable animals have been trained to detect:

  • Various cancers (lung, colorectal, breast, melanoma, bladder)
  • Upcoming epileptic seizures
  • Heart attacks
  • COVID-19
  • Migraines
  • Parkinson’s disease
  • Anxiety attacks

Can Technology Replace Detection Dogs?

With advances in continuous glucose monitoring (CGM) systems, some might wonder if dogs will become obsolete for blood sugar detection. However, many people with diabetes who use both report that:

  1. Dogs sometimes alert before their CGM shows a problem
  2. Dogs can wake sleeping owners when CGM alarms don’t
  3. Dogs provide companionship and emotional support that technology can’t
  4. Dogs don’t require battery changes or have technical glitches

I think the ideal approach combines both: technology for constant monitoring and a dog as backup and emotional support.

The Emotional Component: Beyond Just Detection

There’s something profoundly comforting about having a furry companion who’s constantly looking out for your health. Alert dogs provide:

  • Increased independence for people with diabetes
  • Peace of mind for parents of diabetic children
  • Reduced anxiety about hypoglycemic events
  • Companionship and unconditional love
  • A reason to maintain healthy habits

As one diabetic alert dog owner told me, “Knowing Bella is watching over me while I sleep gives me a sense of security I never had before. She’s not just a tool for managing my diabetes – she’s my guardian angel with four paws.”

Training Your Own Dog: Is It Possible?

While professionally trained alert dogs undergo rigorous programs, some people have had success training their own pets to recognize and alert to low blood sugar. If you’re interested in training your dog:

  1. Collect scent samples when you’re experiencing hypoglycemia
  2. Reward your dog heavily when they show interest in these samples
  3. Begin associating a specific action (pawing, nudging) with the scent
  4. Practice regularly with fresh samples
  5. Consider working with a professional dog trainer experienced in scent work

Remember that self-trained dogs may not be as reliable as professionally trained ones, but many have still proven helpful to their owners.

The Future of Canine Medical Detection

Research into how and why dogs can detect medical conditions continues to advance. Scientists hope that by better understanding exactly what compounds dogs are detecting, they might develop:

  • More sensitive electronic “noses” for medical detection
  • Better training protocols for alert dogs
  • New non-invasive testing methods for various conditions

But for now, our four-legged friends remain some of the most sophisticated “medical devices” available – wrapped in fur and eager to help.

Final Thoughts

The bond between humans and dogs has evolved over thousands of years, but we’re still discovering new dimensions to this remarkable relationship. The ability of dogs to detect low blood sugar is just one example of how these animals continue to surprise and support us.

Whether you have a trained alert dog, are considering getting one, or are just fascinated by canine capabilities, it’s clear that a dog’s nose knows things we’re only beginning to understand.

Have you noticed your dog acting differently when your blood sugar changes? I’d love to hear your experiences in the comments!

how do dogs know you have low blood sugar

Prevention of Hypoglycemia in Dogs

Prevention of hypoglycemia is highly dependent on the cause. For diabetic dogs, routine glucose monitoring after insulin administration is necessary. This may be done at home or in your vet’s office. With puppies and toy breeds, it is important to ensure that these pets are eating a high-quality diet in small, frequent meals to keep their glucose levels regulated. Patients that have underlying disease processes should be monitored frequently at their vet’s office.

How Veterinarians Diagnose Hypoglycemia in Dogs

After examining your pet and obtaining a medical history, your veterinarian will initiate testing. These tests may include:

  • Blood glucose test—a simple bedside test that looks at blood sugar levels only.
  • Chemistry/complete blood count—a more in-depth blood test that checks red and white blood cell levels, glucose level, electrolytes, and organ function. This may be done in the hospital but may also need to be sent out to a laboratory.

Additional testing might be needed, based on initial results and your pet’s clinical signs and medication history:

  • Bloodwork
    • Bile acids—to look for liver damage
    • Hormone-level testing— may include resting cortisol levels or an ACTH stim test to look for Addison’s disease
    • Insulin/glucose ratio test—checks for circulating insulin and glucose levels to look for a potential cancer in the pancreas called an insulinoma
  • Imaging— may include radiographs/x-rays or abdominal ultrasound to check for certain types of cancer, liver disease, adrenal gland disease, or other possible causes.

How dogs can sniff out diabetes

FAQ

How can dogs sense low blood sugar?

Dogs, specifically trained Diabetes Alert Dogs (DADs), can sense low blood sugar by detecting changes in a person’s scent, particularly the increased presence of the chemical isoprene in their breath or sweat as blood sugar drops.

Can dogs sense when someone is diabetic?

Yes, some dogs can sense changes in a person’s blood sugar levels by detecting chemical compounds released during hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar). These changes result in distinct odors that dogs, with their superior sense of smell, can detect in a person’s breath or sweat. It’s thought that dogs may be smelling isoprene, which increases during low blood sugar, and potentially ketones during high blood sugar.

How does a service dog alert for low blood sugar?

Service dogs detect low blood sugar by recognizing the unique scent of a chemical called isoprene that is released when a person’s blood glucose levels drop. While humans cannot detect this specific odor, a dog’s powerful sense of smell, which is estimated to be up to 40 times stronger than a human’s, allows them to notice these subtle changes in a person’s breath or sweat.

Can you train your dog to detect low blood sugar?

Dogs trained to detect low blood sugar are started by being taught to recognize the scent of low blood sugar from puppyhood; serious training begins at 1-3 …Nov 27, 2017